Novel role of aminopeptidase-A in angiotensin-(1–7) metabolism post myocardial infarction
نویسندگان
چکیده
منابع مشابه
Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarction.
Aminopeptidase-A (APA) is a less well-studied enzyme of the renin-angiotensin system. We propose that it is involved in cardiac angiotensin (ANG) metabolism and its pathologies. ANG-(1-7) can ameliorate remodeling after myocardial injury. The aims of this study are to (1) develop mass spectrometric (MS) approaches for the assessment of ANG processing by APA within the myocardium; and (2) invest...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2014
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00911.2013